Protein That Can Stop Cancer Identified
The researchers think that detection of the anti-cancer protein LHPP as a biomarker might allow clinicians to supply better treatment choices.
Researchers have actually found a protein that avoids the unchecked proliferation of cancer cells in the liver. The anti-cancer protein, called LHPP, can also serve as a biomarker for the medical diagnosis and diagnosis of liver cancer, said the research study published in the journal Nature. The occurrence of liver cancer, likewise referred to as hepatocellular carcinoma, is usually identified at a very late stage when the liver is already severely harmed and thus total diagnosis is poor. The scientists think that detection of the anti-cancer protein LHPP as a biomarker might permit clinicians to supply much better treatment choices.
“It stands out that LHPP is present in healthy tissue and completely absent in tumour tissue,” said first author Sravanth Hindupur from University of Basel in Switzerland.
In the study conducted in a mouse design for hepatocellular cancer, the scientists analysed a total of more than 4,000 proteins, comparing them in healthy and tumour tissue.
The research study showed that LHPP emerged as the top favourite.
Re-introduction of the genetic details for LHPP by the scientists was found to prevent the development of tumours and preserve liver function.
“Much like the mouse model, we also saw a striking decline in LHPP levels in tumours of patients with liver cancer,” Hindupur said.